2-OXO-1-PYRROLIDINEACETIC ACID METHYL ESTER Property

Boiling point:

144-148℃ (16 Torr)

Density 

1.131 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.472(lit.)

Flash point:

>230 °F

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform (Sparingly), Methanol (Slightly)

form 

Oil

pka

-1.01±0.20(Predicted)

color 

Colourless

CAS DataBase Reference

59776-88-4(CAS DataBase Reference)

Safety

Hazard Codes 

Xn

Risk Statements 

36/37/38-41-37/38-22

Safety Statements 

26-36-39

WGK Germany 

3

HS Code 

2933.79.8500

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

2-OXO-1-PYRROLIDINEACETIC ACID METHYL ESTER Chemical Properties,Usage,Production

Uses

Methyl 2-Oxo-1-pyrrolidineacetate is used a reagent in the synthesis of benzoquinolizidine and benzoindolizidine derivatives as anti-amnesic agents. It is also used as a a reagent in the synthesis of (acylamino)acridines as choline uptake enhancers.

Uses

Methyl 2-oxo-1-pyrrolidineacetate may be used in the synthesis of N-[(disubstituted-amino)alkyl]-2-oxo-1-pyrrolidineacetamide derivatives.